blood brain barrier

sudhanshu vrati vrati at
Fri Aug 9 07:37:38 EST 2002

Hi !

I am no neurobiologist but I wanted to know a covenient and sure-shot way
of breaking blood brain barrier in neonatal mice.  Would injection of
sucrose or any other "inert" material cause BBB breakage?  How much to
inject and how long before the breakage would be effected? How would I
ensure that the barrier is broken?  I will appreciate receiving feedback
to my above queries.

Many thanks in anticipation.

Sincerely yours,

Sudhanshu Vrati, PhD
Virology Laboratory,
National Institute of Immunology,
Aruna Asaf Ali Marg, JNU Campus,
New Delhi 110 067 India

Phone: 91-11-6162281 / 6188308-12 Ext 396
Fax:   91-11-6162125 / 6177626


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