Sensitisation and receptors

Philippe Coulon coulon-remove- at uni-duesseldorf.de
Fri Dec 20 07:02:37 EST 2002


In news:O2eM9.178$2M.6070 at nnrp1.ozemail.com.au, John H. wrote:
> I'm trying to find some key articles on how receptors alter when
> subjected to large amounts of a neurotransmitter or vice versa. ie.
> becomes highly sensitised when the transmitter is deficient or less
> sensitive when in abundance. Can anyone point me to some good sources
> re this. Web pages okay but prefer journal articles if possible.
> Better still if someone can share their own ideas on this. Promise
> I'll try and respond; intelligently.

Kainate/Glutamate-Receptors desensitise. Hundreds of articles. E.g. Dierkes
et. al J Neurophysiol; Sun et al. Nature
Phil





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