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Rich Murray rmforall at att.net
Wed Dec 25 20:49:38 EST 2002

Dec 25 2002   I welcome a venue for responsible, civil evidence-based
discussion of toxicity issues.  Rich Murray

aspartame: methanol, formaldehyde, formic acid toxicity:
brief review: Murray 12.25.2 rmforall

Rich Murray, MA    Room For All    rmforall at att.net
1943 Otowi Road, Santa Fe, New Mexico 87505 USA   505-986-9103

for 929 posts in a public searchable archive

http://groups.yahoo.com/group/aspartameNM/message/862    long review

formaldehyde & formic acid from methanol in aspartame:
Murray: 12.9.2 rmforall 

It is certain that high levels of aspartame use, above 2 liters daily
for months and years, must lead to chronic formaldehyde-formic acid
toxicity, since 11% of aspartame (1,120 mg in 2L diet soda, 5.6 12-oz
cans) is 123 mg methanol (wood alcohol), immediately released into the
body after drinking (unlike the large levels of methanol locked up in
molecules inside many fruits), then quickly transformed into
formaldehyde, which in turn becomes formic acid, both of which in
time become carbon dioxide and water-- however, about 30% of the
methanol remains in the body as cumulative durable toxic metabolites
formaldehyde and formic acid-- 37 mg daily, a gram every month.
If 10% of the methanol is retained as formaldehyde, that would give 12
mg daily formaldehyde accumulation, about 60 times more than the 0.2
from 10% retention of the 2 mg EPA daily limit for formaldehyde in
drinking water. 

Bear in mind that the EPA limit for formaldehyde in
drinking water is 1 ppm,
or 2 mg daily for a typical daily consumption of 2 L of water.

RTM: ATSDR: EPA limit 1 ppm formaldehyde in drinking water July 1999
5.30.2 rmforall

This long-term low-level chronic toxic exposure leads to typical
patterns of increasingly severe complex symptoms, starting with
headache, fatigue, joint pain, irritability, memory loss, and leading
vision and eye problems and even seizures. In many cases there is
addiction.  Probably there are immune system disorders, with a
hypersensitivity to these toxins and other chemicals.

Confirming evidence and a general theory are given by Pall (2002):
testable theory of MCS type diseases, vicious cycle of nitric oxide &
peroxynitrite: MSG: formaldehyde-methanol-aspartame:
Martin L. Pall: Murray: 12.9.2 rmforall

formaldehyde toxicity:  Thrasher & Kilburn: Shaham: EPA: Gold: Murray:
Wilson: CIIN: 12.12.2 rmforall

"Philippe Coulon" <coulon-remove- at uni-duesseldorf.de> wrote in message news:<atv136$2te$1 at poseidon.uni-duesseldorf.de>...
> Hello NG!
> Since bionet.neuroscience seems overcrowded with non-scientific discussions
> I have been thinking of introducing a new neuroscience newsgroup that is
> limited to scientific exchange. Please mail me if you are interested. If I
> receive enough e-mails, I will forward the list to news.announce.newsgroups
> where it will be open for discussion whether or not to create this NG. If
> you are interested please mail to:
> neuroscience at biochemtech.de .
> --
>  Philippe Coulon

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