membrane lenght constant of rat hippocampal pyramidal cells?
jonesmat at physiology.wisc.edu
Mon Feb 18 18:16:15 EST 2002
"Richard Norman" <rnorman at umich.edu> wrote in message news:<7Acc8.300$Cf5.11114 at news.itd.umich.edu>...
> "Edmund Müller" <edmund.mueller at freenet.de> wrote in message
> news:jims6uc4bgqtgvnqvagu98a9ifje7jpf2o at 4ax.com...
> > Hi NG,
> > My textbooks give a rough estimate like "0.1 to 5 mm in different sort of
> > cells."
> > Could anyone tell me more precisley?
> > Thanks Edmund
For quantitative estimates of electrotonic parameters of hippocampal
and cortical neurons suitable for use in compartmental modeling, I
strongly suggest doing a literature search for:
Here's two to get you started:
Major G., Larkman A.U., Jonas P., Sakmann B. & Jack J.J.B. (1994).
Detailed passive cable models of whole-cell recorded CA3 pyramidal
neurons in rat hippocampal slices. J. Neurosci. 14:4613-4638.
Traub RD, Jefferys JG, Miles R, Whittington MA, Toth K.
A branching dendritic model of a rodent CA3 pyramidal neurone.
J Physiol. 1994 Nov 15;481 ( Pt 1):79-95.
As Richard points out, this whole area of finding "correct" values is
complicated, controversial, and simply does not come in a
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