Basic Neuron Questions

KP-PC k.p.collins at worldnet.att.net%remove%
Sat Apr 12 20:30:10 EST 2003


"BilZ0r" <BilZ0r at TAKETHISOUThotmail.com> wrote in message
news:Xns935C7960D8B02BilZ0rhotmailcom at 202.20.93.13...
| "Didier A. Depireux" <didier at tango.isr.umd.edu> wrote in
| news:b7a69u$jhr$1 at grapevine.wam.umd.edu:
|
| > John H. <johnh at faraway.xxx> wrote:
| >
| >> "Cortical neurons receive 3000-10,000 synaptic contacts, 85% of
which
| >> are asymmetric and     hence presumably excitatory...Absent any
| >> inhibition, a
| >
| > There's a lot more to the story than the number of synapses,
there's
| > also the physical location of the synapse. Those from fibers
arising
| > from thalamus and providing primary input tend to be close to the
cell
| > body, and large. Therefore a single EPSP from a thalamic input is
a
| > lot more effective than a large number of synapses being
activated in
| > the distal part of the dendritic tree. There are also shunting
| > synapses etc, so you need more than just number of synapses
before
| > making these sweeping statements.
| >
| >                               Didier
| >
|
| ...and of course theres more to it that that. The density of
receptors,
| the level of G-protein coupling, the propensity for activting and
| inactivating phosphylation

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k. p. collins





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