Axon collaterals ?

BilZ0r BilZ0r at TAKETHISOUThotmail.com
Tue Dec 16 23:23:07 EST 2003


Not neccasarily (althought I'm rapidly stepping out of my depth)... What 
if there were type II/III mGluRs? Thats what I was originially thinking 
of, monoaminergic synapses and metabatropic receptors. (apart from in the 
case of GABA)

Matthew Kirkcaldie <Matthew.Kirkcaldie at removethis.newcastle.edu.au> wrote 
in news:Matthew.Kirkcaldie-D60CEF.13043217122003
@seagoon.newcastle.edu.au:

> In article <3FDFB0A3.4B1D74 at shaw.ca>, SeeBelow at SeeBelow.Nut wrote:
> 
>> Which suggests that these autapses are likely to be inhibitory, but I
>> don't believe that's necessary. 
> 
> The assertion that they implement negative feedback would suggest they 
> were inhibitory, but in the case of glutamatergic cells (most cortical 
> neurons) they aren't inhibitory, and hence do not implement negative 
> feedback.
> 
>>Does anyone know whether most of them
>> are inhibitory?
> 
> There are no large-scale surveys of autapses that I know of - the 
> difficulty of identifying a synapse as autaptic is immense.  Hence most 
> of the material I have seen is in cultures, and descriptions of 
isolated 
> examples in vivo.
> 
>          Matthew.
> 




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