Axon collaterals ?

John H. johnh at faraway.com.au
Wed Dec 17 09:42:24 EST 2003


No No No please tell me it isn't true. Autapses, just how many mysteries can
one science contain? That's it, you've done it now, my New Year Resolution
is to never read another thing about neuroscience. I'm going to come down to
Newcastle and rip your bloody arms off. Aunty Jack, now that's more my
style.


John H.




"Matthew Kirkcaldie" <Matthew.Kirkcaldie at removethis.newcastle.edu.au> wrote
in message
news:Matthew.Kirkcaldie-D60CEF.13043217122003 at seagoon.newcastle.edu.au...
> In article <3FDFB0A3.4B1D74 at shaw.ca>, SeeBelow at SeeBelow.Nut wrote:
>
> > Which suggests that these autapses are likely to be inhibitory, but I
> > don't believe that's necessary.
>
> The assertion that they implement negative feedback would suggest they
> were inhibitory, but in the case of glutamatergic cells (most cortical
> neurons) they aren't inhibitory, and hence do not implement negative
> feedback.
>
> >Does anyone know whether most of them
> > are inhibitory?
>
> There are no large-scale surveys of autapses that I know of - the
> difficulty of identifying a synapse as autaptic is immense.  Hence most
> of the material I have seen is in cultures, and descriptions of isolated
> examples in vivo.
>
>          Matthew.





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