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need help : Hodgkin & Huxley matlab simulation

eldad mittelman mittelma at ee.bgu.ac.il
Thu May 8 01:13:43 EST 2003


thanks a lot,
I notice how much of a difference there is indeed.

Eldad.


"r norman" <rsnorman_ at _comcast.net> wrote in message
news:lhmcbvori8s7liq1fdthm3m95nmsnrdmc6 at 4ax.com...
> On Mon, 5 May 2003 13:34:43 +0200, "eldad mittelman"
> <mittelma at ee.bgu.ac.il> wrote:
>
> >I wrote a matlab simulation for  Hodgkin & Huxley model, when I am giving
a
> >current stimulation I can see a change in the membrance voltage.
> >how can I determine if the change is or is not an action potential?
> >I need the computer to be able to recognize the action potential and that
> >way I can write a program that find the stimulation threshold.
> >
> >thanks,
> >Eldad Mittelman.
> >mittelma at ee.bgu.ac.il
>
> Use your simulation to generate two responses, one to a stimulus below
> threshold and one to a stimulus above threshold.  You should see
> rather obvious differences in the appearance of the two responses.  It
> shouldn't be that hard to figure out a characteristic that is easy to
> measure automatically.
>
> Of course, if you are investigating things like changes in channel
> density or ion concentration you can get into areas of relatively
> graded active response so that there is no clear-cut discontinuous
> change in the response.  However, under almost all relatively normal
> circumstances, the action potential is called "all-or-none" for a good
> reason.
>
> Yes, I am being somewhat evasive in my answer because I suspect this
> may be a class assignment.  So let me know what you are trying and I
> will give you more help.
>





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