Neuron function question

Kalman Rubinson kr4 at nyu.edu
Fri Oct 24 13:26:02 EST 2003


On Fri, 24 Oct 2003 18:18:22 GMT, "David Todtman"
<dtodtmanREMOVETHHIS at shaw.ca> wrote:

>> questions, but for a few I may be able to help you out a bit.
>You helped a lot.  Thank you.  Here are some questions related to your note.
>
>First, thanks to you and Kal, I got a crucial answer:  the metabotropic
>receptors accept binding molecules on the element of the receptor that is
>outside the cell.  And, the recepor part inside the cell releases the 2nd
>messenger molecules  (e.g., calcium).
>
>Does this mean that neurotransmitters, for example, can be considered "1st
>messenger molecules"?  What seemed odd--maybe my mind likes things neat and
>tidy--is that my book only mentions "2nd messenger molecules" but there is
>no reference to "1st."  My mind thinks if there is a "2nd" there must be a
>"1st."

By default and reference, yes, but the term is not in general use.

>Finally, could you please give the full-word equivelant for cAMP and cGMP.

cyclic AMP: adenosine 3',5'-cyclic monophosphate
cyclic GMP: guanosine 3',5'-cyclic monophosphate

Kal



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