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Neuron function question

David Todtman dtodtmanREMOVETHHIS at shaw.ca
Fri Oct 24 21:58:21 EST 2003

Thank you for the excellent reminder.  Our capacity for reduction can lead
us to forget that these processes are immanent in the ensemble as a whole.

"KP_PC" <k.p.collins at worldnet.att.net> wrote in message
news:snhmb.191803$0v4.14892882 at bgtnsc04-news.ops.worldnet.att.net...
> "David Todtman" <dtodtmanREMOVETHHIS at shaw.ca> wrote in message
> news:Dugmb.168102$6C4.33699 at pd7tw1no...
> | > 1.  Any receptor-mediated mechanism might
> | > be modulated by co-factors or by other cellular
> | > mechanisms (like other metabotropic receptor
> | > events).  In general though, you might think of it
> | > as a population effect.  If more (or fewer) are
> | > simultaneously activated or serially activated,
> | > the internal effect can be modulated proportion-
> | > ately Oh perfect!   I am getting this picture.
> |
> | I think I just have a few questions left at this point
> | and then I'll stop prevailing on your time.
> |
> | Am I correct to understand that the metabotropic
> | process does not directly cause the action
> | potential?  My question here is about the other
> | end of the cell:  I gather that ionotropic action
> | causes the vesicles to migrate to the cell wall to
> | release neurotransmitters.  So, I think this means
> | that metabotropic action does not directly cause
> | the vesicular process.  It (metabo.) may come
> | into play with regard to modulating the production
> | of neurotransmitters within the cell (which then are
> | deposited into the vesicles awaiting release).  Eh?
> |
> | Good wishes,
> | David
> There's nothing that's 'separable'. Everything in-
> there is doing the one thing, but think of it in terms
> of your everyday experience - to achieve any 'goal',
> one must procede along a 'curved' path, first estab-
> lishing relatively-fundamental capabilities, and, as
> these are established, using them to achieve the
> next more-close approach to the goal.
> For instance, one who has the goal of becoming
> a Professional Football Player doesn't just say,
> "I will be a professional football player." Instead,
> at a Young age, he exercises his body and pract-
> ices Football, growing more experienced with
> increasing hours of practice. The hours of prac-
> tice establish skills that are useful in playing Foot-
> ball - the fundamental capabilities which are as
> 'tools' with respect to the goal of becoming a
> Professional Football Player.
> So, too, the nervous system cannot just 'say',
> "I'm going to process information by selectively-
> tuning ionic energydynamics." The nervous system
> must, first; establish more-fundamental capabilities
> through which it can, then, selectively tune ionic
> energydynamics.
> So, in the selective tuning of ionic energydynamics,
> the more-fundamental stuff is right-there, a part of
> the whole.
> There's no 'separating' anything [at least not
> within 'normal' nervous system function].
> It's part of why nervous systems are so Amazing.
> Their 'orchestration' is Exquisitely all-encompassing.
> So much so that, look at anything within the nervous
> system, and, through the chosen 'lens', one can see
> everything else within the nervous system.
> This is be-cause everything within nervous systems
> does only one thing: 'grasp' the one-way flow of
> energy from order to disorder that is what's de-
> scribed by 2nd Thermo [WDB2T], and 'climb' the
> energy-gradient, inherent, in a globally-orchestrated
> way.
> So, pick anything within a 'normal' nervous system,
> see how it handles WDB2T, and that discloses its
> integrated 'role' with respect to everything else within
> that nervous system.
> My "everyday experience" analogy, above, is of
> limited usefulness in one important way with re-
> spect to nervous system function. 'Elements' in
> 'normal' nervous system function are not like people
> in interaction - they don't 'wage-war' against each
> other. They're all 'good-players' that all work to-
> ward the same 'goal' - even the cells that die during
> the developmental wiring-up of a nervous system
> die 'willingly' be-cause doing so is their way of
> working toward the one 'goal' [that is, the devel-
> opment of cortical features such as "stripes"
> occular-dominance columns, etc., is =not= a
> result of 'competition'. Rather, such features are
> the result of exquisite co-operation toward the
> achievement of the =one= 'goal' [for those who
> have AoK, the 'goal' is, of course, TD E/I-mini-
> mization, which can be further reduced, as above,
> to the 'grasping' and 'climbing' of WDB2T.]
> It's 'funny', what nervous systems got-right, so
> Beautifully, eons ago, organisms still routinely
> botch.
> Perhaps, through accumulating understanding of
> nervous system information-processing dynamics,
> Humans will be able to learn the lesson, inherent?
> Anyway, I hope what's here helps with your query.
> There's nothing that's 'separable' in-there. Every-
> thing within nervous systems co-operates toward
> the one 'goal'.
> It's very-useful to keep this in-mind as one considers
> anything within nervous systems and their functioning.
> Cheers, ken [k. p. collins]

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