Copper & Alzheimer's Disease

tintinet tintinet1 at iwon.com
Tue Sep 2 06:26:52 EST 2003


rsymes <rsymes at dodo.com.au> wrote in message news:<3F5402CD.7B6B1F64 at dodo.com.au>...
> Everyone seems concerned about limiting their copper intake by drinking distilled
> water but I think its more sensible to cut down on the cholesterol intake.

Cholesterol is a substance one's body makes for itself. Just cutting
down or eliminating sources of cholesterol in one's food will not
necessarily produce low levels in one's body.



 When the
> body is overloaded by any particular chemical, either organic or inorganic, it can
> result in problems which may be compounded by a second chemical. Take the once
> popular solvent carbon tetrachloride use by dry cleaners. If you drank alcohol
> after using this solvent you could die very soon after due to the interaction with
> the alcohol. The same quanity of alcohol without exposure to the solvent would be
> harmless. Which of the two is it better to avoid exposure to?
> Thats an extreme example but going back to copper, its not just in water, its in
> many foods. Most of the common nuts like pecans, hazel nuts and walnuts contains
> 1-1.3 mg Cu per 100g and brazil nuts contain up to 2.3 mg per 100g.
> Considering copper consumption is unavoidable and in fact a requirement for
> metabolism of iron, development of red blood cells plus a host of other things, its
> seems to me that its the cholesterol which is the problem.
> 
> 
> 
> 
> Ian Goddard wrote:
> 
> > Copper link to Alzheimer's disease:
> > http://www.newscientist.com/news/news.jsp?id=ns99994045
> >
> > The abstract:
> > http://www.pnas.org/cgi/content/abstract/1832769100v1
> >
> > Proc. Natl. Acad. Sci. USA, 10.1073/pnas.1832769100
> >
> > Trace amounts of copper in water induce beta-amyloid plaques and
> > learning deficits in a rabbit model of Alzheimer's disease
> >
> > [authors and affiliations cut for brevity, see link above]
> >
> > Despite the crucial role played by cholesterol and copper in nutrition
> > and normal brain function, recent evidence indicates that they may
> > both be important factors in the etiology of Alzheimer's disease (AD).
> > Here we provide critical evidence for the role of cholesterol and
> > copper in AD by showing that the addition of trace amounts of copper
> > (0.12 ppm) to water given to cholesterol-fed rabbits can induce
> > beta-amyloid (Abeta) accumulation, including senile plaque-like
> > structures in the hippocampus and temporal lobe, and can significantly
> > retard the ability of rabbits to learn a difficult trace conditioning
> > task. The Abeta deposits do not affect the ability of rabbits to
> > detect or respond to the training stimuli nor to learn a simpler delay
> > conditioning task. Trace amounts of copper in drinking water may
> > influence clearance of Abeta from the brain at the level of the
> > interface between the blood and cerebrovasculature and combined with
> > high cholesterol may be a key component to the accumulation of Abeta
> > in the brain, having a significant impact on learning and memory.
> > Cholesterol-fed rabbits have at least 12 pathological markers seen in
> > AD, suggesting that the cholesterol-fed rabbit is a good animal model
> > for studying AD.
> >
> > >  Also see:
> > >
> > >  Aluminum and Alzheimer's disease:
> > >http://www.google.com/groups?selm=gq8havshkhetd6s78ctbgvc8iev0gtma1n%404ax.com
> > >
> > >  Iron and Alzheimer's disease:
> > >http://www.google.com/groups?selm=bhfmiv867s916mglu8ioerf60ninn8b2hs%404ax.com
> > >
> > >  Mercury and Alzheimer's disease:
> > >http://www.google.com/groups?selm=3af37029.2307577%40news.erols.com
> > >
> > >
> > >  http://IanGoddard.net/journal.htm
> > >
> > >  "To lengthen thy life, lessen thy meals." Ben Franklin
> > >
> > >  Ongoing CR-monkey-study update: "In the monkeys...those on
> > >  reduced feeding since the study started are dying at a rate
> > >  that is about half that of the monkeys receiving a full food
> > >  ration." Associated Press: Eating less may extend human life.
> > >  August 1, 2002 : http://www.msnbc.com/news/788746.asp?0si=-
> > >
> > >



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