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Serotonin Re-uptake

ZaLTaR ZaLTaR666 at Hotmail.com
Wed Feb 18 14:11:07 EST 2004

Thnx !

"r norman" <rsn_ at _comcast.net> wrote in message
news:ogr6309a583nll65nr1nsva79kbujks2no at 4ax.com...
> On Wed, 18 Feb 2004 13:07:11 +0100, "ZaLTaR" <ZaLTaR666 at Hotmail.com>
> wrote:
> >Is it possible to use a Re-Uptake compound in combination with serotonin
> >refull the serotonin levels in the brain after
> >the release of this substance ?
> >
> Your question is far too general to really answer.  Yes, serotonin
> reuptake is an important mechanism to re-establish presynaptic
> serotonin stores after release.  The presynaptic terminal also
> synthesizes serotonin and that also refills the system.
> The real question is why you would suggest alterning the natural
> process.  If things are working normally, then there is no need to
> change anything.  If things are going wrong, then you have to look at
> just what the problem is before trying to fix it.  The problem could
> be failure to synthesize it, problem to release it, problem to respond
> to it postsynaptically, problem to recycle it. Usually, a "deficiency"
> in serotonin response is treated with a reuptake inhibitor, not a
> reuptake stimulator. By inhibiting reuptake, you make the serotonin
> that is released stay longer in the synaptic gap and therefore exert
> more of an effect.

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