regularity of spike series

mat mats_trash at hotmail.com
Sat Jan 24 07:46:00 EST 2004


y.k.y at lycos.com (yan king yin) wrote in message news:<72de81ae.0401231727.6564dfcf at posting.google.com>...
> Spike trains obtained from a single neuron is the
> result of dendritic integration of ~1000 to 100,000
> of other neurons' inputs. What kind of information can
> autocorrelation of a few spike trains reveal? Probably
> very little...
> 
> I guess your research will be more fruitful if you
> focus more on single neuron information processing.
> 
 These are not single neuron spikes they are field potentials.  I'm
using an in vitro model of epileptic activity by perfusing magnesium
free artificial CSF.  What I would like to establish is whether there
is any degree of regularity to these trains of depolarizations
(~6-10/min) and see if this is altered when I co-perfuse drugs across
the cortex.

Autocorrelograms can reveal simple regularities in spike trains, e.g.
if many spikes are followed by another one at 30s then you'll get a
bump in the autocorrelogram.  But since I've not found anything like
that what I need is a measure of higher-order patterns, though I'm not
sure even if I find one how to interpret that since it might be highly
non-intuitive.



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