On The Engram

kenneth collins kenneth.p.collins at worldnet.att.net
Sat Jan 15 00:27:21 EST 2005

"kenneth collins" <kenneth.p.collins at worldnet.att.net> wrote in message 
news:RR_Fd.19316$w62.19055 at bgtnsc05-news.ops.worldnet.att.net...
> [...]

> If the hypothesis is correct, it'll open
> the door to a whole new approach
> to all facets of molecular dynamics,
> and, of course, the thing to do =first=
> will be to thoroughly analyze the depths
> of all that's correlated to the hypothe-
> sized 3-D-Geometry "correlations".
> [...]

For instance, it's in the hypothesis that
the endoplasmic reticulum exhibits(?)
a molecularly-graded constitution that
should be readable.

Do folks see why this is necessary?

The endoplasmic reticulum is "folded".

In the hypothesis, this "folded-ness" is
what is established by, and what, in turn,
facilitates the tuning of, "the genome",
as neural activation is experienced, the
net result being the maintenance of neur-
on's Topologies, probably including
deep "memory"-configuration shifts.

The essence of it is that it's the Geom-
etry of the endoplasmic reticulum that
Topologically-"grades" ["marks" with
respect to topological-"gradient" [with
respect to topological-locus]] protein
and other constituent synthesis. So this
intra-endoplasmic-reticulum "gradient"
should be observable in-experiment.
It's probably extremely-subtle -- like
a macromolecular "charge" gradient.

This sort of "marking" functionality is
an absolute necessity with respect to
neuronal Topology, and the actions
that the hypothesis attributes to the
=interaction= of the endoplasmic re-
ticulum with "the genome" seems per-
fectly situated to carry it out.

[Remember, "the genome" cannot do
it by itself because the deep necessity
is the coupling of "the genome" with
neuronal activation experience [which,
with respect to the set of all neurons,
is what tunes nervous system function
to the net experience that an organism

So the hypothesis will be Verified, in
some general form. But it will also be
greatly-refined while the hypothesis is
being investigated..

k. p. collins 

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