[Neuroscience] Re: What exactly are neuromodulators?

Jeff kidsdoc2000 at hotmail.com
Mon May 8 22:02:33 EST 2006


"alex" <alex at catbull.com> wrote in message 
news:1147035816.854075.55970 at j33g2000cwa.googlegroups.com...
> Are neuromodulators secreted by neurons and do they bind to receptors
> of the post synaptic membrane? So what is the difference between them
> and neurotransmitters then?

Neuromodulators are longer lasting, don't work through synapses (rather, the 
neuromodulators are squirted out around the axon into the intercellular 
fluid or go through cell membranes like nitric oxide and carbon monoxide), 
modulate the activity of neurons rather than inhibit or excite them.

> Do they affect neurontransmitters? If yes,
> how do they do? Are drugs (like opiates, amphetamines) neuromodulators
> or neurotransmitters?

No, they're drugs.

> Thanks and kind regards, alex

Jeff 




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