[Neuroscience] Re: Neuronal activity in the brain
(by tofijoy from yahoo.co.in)
Sat Oct 28 11:33:21 EST 2006
Thanks, Dr. Norman. I am sure these references will help.
"r norman" <r_s_norman from _comcast.net> wrote in message
news:67g2k2div0460pjeq49fh8rfgfs3f0g4f4 from 4ax.com...
> On Fri, 27 Oct 2006 08:50:04 +1000, Matthew Kirkcaldie
> <m.kirkcaldie from removethis.unsw.edu.au> wrote:
>>In article <ehqgcn$9r7$1 from mailhub227.itcs.purdue.edu>,
>> "Fijoy George" <tofijoy from yahoo.co.in> wrote:
>>> In fact, I am a student (in
>>> Computer Science) currently working on the EEG/MEG neural source imaging
>>> problem, and I wanted to know how to correctly simulate activation
>>> on the cortical surface.
>>I sympathise with your problem! Unfortunately I think there's little
>>available guidance to suggest a "correct" way, because we don't know
>>what kinds of neuronal activity produce fMRI signal. Are you wanting to
>>map the electrical EEG domain to the fMRI domain? That sounds like an
>>interesting problem and I will have a dig around to see what I can turn
>>up. Maybe Dr Agmon or Dr Norman could suggest some resources. My first
>>thought is the Brain Dynamics group here in Sydney, Australia - they
>>have produced models of EEG power spectra based on simple anatomical
>>properties of bulk cortical tissue. I don't think they have applied it
>>to correlation with fMRI though - although the members do use fMRI in
>>Hope that helps - it's much easier to know how to advise when you say
>>what you're trying to achieve!
> It's rather out of my own experience, but you could start with
> Nikos K. Logothetis, Jon Pauls, Mark Augath, Torsten Trinath and Axel
> Nature 412, 150-157 (12 July 2001)
> "Neurophysiological investigation of the basis of the fMRI signal"
> Jueptner M, Weiller C
> "Review: does measurement of regional cerebral blood flow reflect
> synaptic activity? Implications for PET and fMRI."
> Neuroimage. 1995 Jun;2(2):148-56.
> Arien J. Smith , Hal Blumenfeld , Kevin L. Behar , Douglas L. Rothman
> , Robert G. Shulman , and Fahmeed Hyder
> "Cerebral energetics and spiking frequency: The neurophysiological
> basis of fMRI "
> PNAS | August 6, 2002 | vol. 99 | no. 16 | 10765-10770
> David Attwell and Costantino Iadecola
> "The neural basis of functional brain imaging signals"
> TRENDS in Neurosciences Vol.25 No.12 December 2002
> S. Sheth, M. Nemoto, M. Guiou, M. Walker, N. Pouratian, A. Toga
> "Linear and Nonlinear Relationships between Neuronal Activity, Oxygen
> Metabolism, and Hemodynamic Responses"
> Neuron, Volume 42, Issue 2, Pages 347-355
> Robert G. Shulman1, Douglas L. Rothman1,2, Kevin L. Behar3 and Fahmeed
> "Energetic basis of brain activity: implications for neuroimaging"
> TRENDS in Neurosciences Vol.27 No.8 August 2004
> P M Matthews and P Jezzard
> Functional magnetic resonance imaging
> Journal of Neurology Neurosurgery and Psychiatry 2004;75:6-12
> There is a lot more, but these, plus the references in them, will keep
> you busy for a while.
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