[Neuroscience] Re: SSRIs bind to post-synaptic 5-HT receptors and
function as competitive antagonists?
Glen M. Sizemore
(by gmsizemore2 from yahoo.com)
Wed Nov 19 19:21:49 EST 2008
"r norman" <r_s_norman from _comcast.net> wrote in message
news:1f38i4ptqiifib4vmg6d6elrrm30t0t6s0 from 4ax.com...
> On Wed, 19 Nov 2008 05:26:55 -0500, "Glen M. Sizemore"
> <gmsizemore2 from yahoo.com> wrote:
>>"Glen M. Sizemore" <gmsizemore2 from yahoo.com> wrote in message
>>news:49234c1f$0$26361$ed362ca5 from nr5.newsreader.com...
>>> Someone I know claims that SSRIs bind at post-synaptic serotonin
>>> receptors, and function as competitive antagonists. Anyone know anything
>>> about this? Thanks ahead of time...
>>Correction: SOME SSRIs
> Could (s)he be thinking of the action of pindolol which is sometimes
> used in conjunction with SSRIs?
Hi Dr. Norman,
I can now answer my own question, but I'll post the provisional answer for
those that might be interested, and I'll provide a reference for those that
are interested. Some SSRIs do, indeed, bind at the 5-HT2c receptor, and
function as competitive antagonists.
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