[Neuroscience] Re: Equation that explains the behaviour of a circuit in voltage clamp

Bill.Connelly via neur-sci%40net.bio.net (by connelly.bill from gmail.com)
Sat Apr 4 20:30:36 EST 2009


On Apr 5, 10:51 am, r norman <r_s_nor... from comcast.net> wrote:
> On Sat, 4 Apr 2009 14:57:34 -0700 (PDT), "Bill.Connelly"

> Whether or not there is Rs, the membrane current is still Im = V/Rm +
> C dV/dt where V is the true transmembrane voltage, not a measured
> voltage contaminated by the I * Rs term.

Ohhhhh... okay then.... So

Im = Vm/Rm + C dVm/dt
And Vm... well
dVm/dt=(Vcmd-Vm)/(Rs*Cm)

No, that still isn't right, because Vm tends absolutely towards Vcmd.

Somehow I need to take into account Im*Rs

I'm sorry I'm being stupid here. I'm trying to grasp what you're
saying, I'm just not very good at the math and the physics.


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