[Neuroscience] re: Urethane anaesthesia? (Bill)

Mick Craig via neur-sci%40net.bio.net (by mick6116 from googlemail.com)
Tue Mar 23 05:13:52 EST 2010


Hi Bill,

I use urethane from time to time. It seems to be fairly stable over time but
I find that, in mice anyway, there's quite a fine line between the mouse
being too light and too deeply anaesthetised (and thus dying). I normally
start with a loading dose of 1.6g/kg and with top-ups around 10% of the
initial injection volume, if required.

Best,
Mick


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