EPM

PRESTWOOD.A at CALC.VET.UGA.EDU PRESTWOOD.A at CALC.VET.UGA.EDU
Mon Oct 16 06:38:06 EST 1995


Fred asked about symptoms, treatment for equine protozoal myelitis.

EPM is caused by Sarcocystis neurona, a protozoan whose definitive 
host is unknown.  It infects several animals others than horses.  
Symptoms are related to the nervous system and can vary. Other 
diseases also afflict the CNS of horses, so diagnostic tests must be 
performed to properly diagnose the infection.

The reference given below may help:
C.K. Fenger. 1995. Treating equine protozoal myelitis. The Horse, 
June, p18, 20. recommended the following treatment.

Administer trimethoprim-sulfamethoxazole at the rate of 15 - 30 mg/kg 
(about 7-15 DS tabs/1000 lbs BWT twice daily) AND 1.0 mg/kg daraprim 
(20 tabs) once daily for 3 to 6 months via a dose syringe.  Anti-
inflammatory drugs, folic acid, and vitamin E may be needed in 
addition to the other drugs.  

Dr. Fenger is located at the University of Kentucky's Equine Center.

You should consult your local equine veterinarian for additional 
information on diagnosis (there is a diagnostic test available at the 
Univ of Ky) and treatment.
A.K. Prestwood
e-mail prestwood.a at calc.vet.uga.edu



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