John:

Stephen Kayes skayes at USAMAIL.USOUTHAL.EDU
Thu Aug 7 09:44:38 EST 1997


John:

I am not exactly sure what criteria would satisfy your curiosity.  But in the short
answer, yes , there is.  The primary example that comes to mind is a mouse known as
the SCID mouse (SCID stands for severe combined immunodeficient disease) and
essentially these mice have no immune system of any kind (boy-in-the-bubble
syndrome).  One way these   very useful research animals are used is to transfuse them
with human lymphocytes (the cells of the human immune system) and then  infect the
mice with the AIDS virus to look at what happens when human cells become infected. 
Because the mice have no immune system, they can not reject the human cells which
then become established in the mouse and give a minimal representation of the human
immune system.  Hope that begins to answer your question.

Steve Kayes

                    ==========================
Stephen G. Kayes, Ph.D                       Ofc: (334) 460-6768
Professor                                                   FAX: (334) 460-6771
Structural and Cellular Biology; 2042 MSB
University of South Alabama College of Medicine
Mobile, AL  36688-0002             

E-mail: kayes at sungcg.usouthal.edu
                    ==========================

>>> John V LeDuc Jr <leducjjr at hal-pc.org> 8/6/97  11:07 pm >>>
Please educate me.

Is there a successful human-animal clone process in place?
(Transplanting human DNA or other such material into either a grown
animal or animal
embryo)

If so, what is the likelihood of animal-only diseases adapting to the
"new" environment (the "manimal") and invading "true" humans?

Thanks,

John
<mailto: leducj at epenergy.com>





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