Advice sought on treating Angiostrongylus costaricensis
Torsten Mark Kowal
tmkowal at hondutel.hn
Thu Feb 28 10:37:57 EST 2002
I am a British forester resident in Honduras. I was recently operated on
for abdominal/intestinal angiostrongyliasis due to infection of
Angiostrongylus costaricensis. A 12 inch section of intestine was found to
suffer granulomatous tissue reaction. I am under the supervision of Dr
Nahim Nasralla of the Evangelical Hopsital, Siguatepeque <Nahimnaz at aol.com>
I am now recovering and seeking information on the best compound to
eradicate any remaining larvae or adult nematodes from my body, but medical
treatment I understand is notoriously difficult. I really want to
eliminate any further risk after traumatic surgery, which I wouldn't want
I am taking albendazole (200 mg twice a day for 5 days) but understand that
this is not the drug of choice for rather, Thiabendazole/Tiabendazole is
the drug of choice against strongyloidiasis caused by Angiostrongylus
costaricensis. But the latter is not available in Honduras and is known to
cause severe side effects.
I believe Mebendazole can also act on the nematode, but only weakly. The
experimental anti-helmintic drug
cyclodepsipeptide PF1022A has also been studied, but I have no idea if this
is approved and available.
In the absence of Thiabendazole, I believe that the Albendazole course
could be followed by a course of Mebendazole.
Do you have any advice as to latest best practice in treating A.
costaricensis and whether the Albendazole + Mebendazole treatment is
likely to be effective.
Mr Torsten Mark Kowal
Dirección postal: Apartado 189, Siguatepeque, Honduras, América Central.
Email: Torsten Mark Kowal tmkowal at bigfoot.com y tmkowal at hondutel.hn
Tels.: + (504) -7730686; + (504)-7734862; Fax. + (504) -7734863
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