Bioresearch Online Newsletter

Bioresearch Online newsletter at VERTICAL.NET
Wed Sep 1 15:36:57 EST 1999

Bioresearch Online Newsletter
Volume 2   Issue 45
Tuesday, August 31, 1999

The recent proposal put forth by Harold Varmus and others for electronic
publishing of biomedical research at first glance looked like the answers to
researchers prayers -- timely and free access to research findings and
all at your fingertips. However, the latest version seems to have
lost some of the luster of the earlier proposal, giving journal editors
control over the content as well as the timing of the on-line papers.

Bioresearch Online would like to provide a place for researchers to post
their findings when they think they're ready, and not wait for journal
editors' stamp of approval. We reach tens of thousands of researchers monthly
from around the world, and have discussion groups and chat lines that can
provide immediate feedback on your ideas.

Check out the Call for Papers on the homepage, and give us your thoughts in
the Discussion Forum.

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******** Bioresearch Online’s Weekly Selection: ********

Methods in Plant Biochemistry and Molecular Biology by William V. Dashek
Modern plant science research currently integrates biochemistry and molecular
biology. This book highlights recent trends in plant biotechnology and
molecular genetics, serving as a working manual for scientists in academic,...
Our price: $95.00  To read more and purchase this book, visit:

***** FEATURED ARTICLES selected by Laura DeFrancesco *****

1) House Makes Deep Cuts in Federal R&D
2) Mouse Model for Anxiety Disorders Created
3) MicroArrays Provide Clues on Aging


1) House Makes Deep Cuts in Federal R&D
The economy may be booming, but research funding continues to limp along. For
an analysis of the prospects for R and D funding for next year, check out the
report by Kei Koizumi, Senior Program Associate, American Association for the
Advancement of Science.

2) Mouse Model for Anxiety Disorders Created
Transgenic mice figure prominently in the research news of the week. Scientists
from the University of Zurich developed a mouse model for anxiety by knocking
down the number of GABA receptors in the hippocampus and cerebral cortex.
Meanwhile, researchers in North Carolina have made mice schizophrenic by
reducing the NMDA receptors.

3) MicroArrays Provide Clues on Aging
Microarrays take center stage this week as well. Researchers from the
University of Wisconsin, Madison used DNA microarrays to gain important
information about gene expression that accompanies aging and the delay of aging
observed with caloric restriction. And more chips for researchers hit the
streets as Affymetrix rolled out its rat chip this week, and Ciphergen
announced a deal with the NIH to make its ProteinChip available to academic and
government researchers.

******** EDITOR'S CHOICE PRODUCTS ********

1) Apochromatic Stereomicroscope
2) Assay Kits
3) Single-Channel Pipette


1) Apochromatic Stereomicroscope
With 100% apochromatic correction throughout the image-forming optics, Leica
Microsystem's MZ APO stereomicroscope is suited for observing transparent, low-
contrast objects.  This stereomicroscope has a modular design and is available
with a wide selection of accessories for all tasks in investigation and

2) Assay Kits
Alexis Biochemical's whole blood assay kits were designed for the detection of
human cytokines and for determining the immunocompetence of a patient. Cytokine
levels are measured directly from heparinized blood, and all cellular and serum
influences are thus providing an estimation of in vivo cytokine levels.

3) Single-Channel Pipette
Capable of handling dispensing tasks in the range of 0.1 µl to 5 ml, the
VoluMate single channel pipette from Mettler Toledo is available in seven

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Join the Bioresearch Online community. We welcome your input. Drop me a line
at ldefrancesco at or visit the discussion forums.


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