nitrogenase

Carl Pike carl.pike at fandm.edu
Wed Apr 27 07:33:53 EST 2005


It is well-known that molecular oxygen inhibits nitrogenase.  I
assume that this may have something to do with causing oxidation of
the metals (Mo and Fe) that are in the enzyme.  A student asked if
the inhibition was reversible or irreversible.  No source that I have
consulted answers this question, although one used the word
"denaturation" in reference to the oxygen effect on the protein.

Any thoughts?

Thanks

Carl
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