DHFR causes weird phenotypes ?

suter at VAX.mpiz-koeln.mpg.d400.de suter at VAX.mpiz-koeln.mpg.d400.de
Tue Jan 25 08:54:27 EST 1994


Dear netters,

a colleague of mine transformed tobacco with constructs containing 
the DHFR gene (encodes mtx resistance ?).
He now finds in many cases changed flower morphology, that is a doubling
and/or fattening of male reproductive organs. This is hereditary and in second
generations independent of whether the antibiotic is present in the 
medium or not.
Due to his controls, he presumes that it has to do with the DHFR gene.

Could anybody give an explanation for this effect ? Can DHFR cause such
effects in flower development ?

On the other hand, you can also send me lots of money (address indicated
below).

cheers,
clemens
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Clemens Suter-Crazzolara, PhD
Max-Planck-Institut fuer Zuechtungsforschung
Abteilung Genetische Grundlagen der Zuechtungsforschung
Carl-von-Linne Weg 10,        D-50829 Koeln, Germany
Tel.xx49.221.5062-221    Fax.-213      e-mail: suter at vax.mpiz-koeln.mpg.d400.de
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		alas, i can only contact the newsgroups by e-mail
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