[Plant-signal-transduction] Postoctoral Positional - Functional Genomics of Plant Disease Defense

Roger Wise rpwise at iastate.edu
Thu Mar 30 13:06:34 EST 2006


Postdoctoral Position Available
Iowa State University
Functional Genomics of Plant Disease Defense

A postdoctoral research position is available immediately in the Iowa 
State University Center for Plant Responses to Enviromental Stresses 
under the direction of Drs. Roger Wise and Steve Whitham.  The 
overall goals of the NSF-Plant Genome project "Functional Genomics of 
Plant Disease Defense Pathways" 
http://nsf.gov/awardsearch/showAward.do?AwardNumber=0500461 are to 
utilize functional genomics tools and resources available to barley, 
rice, and the model dicot Arabidopsis thaliana, to accelerate 
comparative analysis of disease defense pathways important in 
agriculture.

Candidates will work with a team responsible for molecular, genetic, 
and functional characterization of gene-specific sequences associated 
with and required for R-gene mediated resistance responses using 
barley powdery mildew as a model system. Approaches include 
utilization of the 22K Affymetrix Barley1 GeneChip to characterize 
the transcriptional networks regulated during powdery mildew induced 
programmed cell death and subsequent high-throughput reverse genetic 
systems in barley and Arabidopsis to functionally validate candidate 
genes in resistance pathways of both monocot and dicot plants.  All 
of the above approaches will be facilitated by well-characterized, 
high-resolution, recombinant mapping populations, accelerated 
cell-death mutants, RNAi and TILLING silencing systems, BAC, cosmid, 
and cDNA library resources.

Funding is available up to three years. Salary is commensurate with 
experience.  Ph.D. required in genetics, molecular biology, plant 
physiology, plant pathology or related field.  Experience in 
bioinformatics/computational/statistical analysis, single-cell 
transcript profiling, RNAi mediated gene silencing, cell biology, 
and/or high-throughput gene mapping is desirable.  Highly motivated 
individuals should send curriculum vitae, research interests, and 
reprints to the address below:

- Name, e-mail, address, phone, and fax no. of three references 
should be included -

Dr. Roger Wise, USDA-ARS
Department of Plant Pathology
Iowa State University
Ames, IA, 50011-1020
rpwise at iastate.edu
Phone: 515-294-9756
Fax: 515-294-9420
http://wiselab.org/ ; http://plexdb.org/

Recent Literature:
Shen, L, J Gong, RA Caldo, D Nettleton, D Cook, RP Wise, and JA 
Dickerson. 2005. BarleyBase-an expression profiling database for 
plant genomics. Nucleic Acids Research 33: D614-D618.

Caldo, RA, D Nettleton and RP Wise. 2004. Interaction-dependent gene 
expression in Mla-specified response to barley powdery mildew. Plant 
Cell. 16: 2514-2528.

Close, TJ, S Wanamaker, R Caldo, SM Turner, DA Ashlock, JA Dickerson, 
RA Wing, GJ Muehlbauer, A Kleinhofs and RP Wise. 2004. A new resource 
for cereal genomics: 22K barley GeneChip comes of age. Plant 
Physiology 134: 960-968.

Halterman, D and RP Wise. 2004. A single amino acid substitution in 
the sixth leucine-rich repeat of barley MLA6 and MLA13 alleviates 
dependence on RAR1 for disease resistance signaling. Plant Journal 
38: 215-226.

Iowa State University is an Equal Opportunity/Affirmative Action Employer.
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