protein design using computational methods
sjhg9320 at uxa.cso.uiuc.edu
Fri May 17 15:06:24 EST 1991
wrp at biochsn.acc.Virginia.EDU (William R. Pearson) writes:
> I do not believe that there are any "well-known cases" of proteins
>of very similar sequence (>50% identity) folding into different
>conformations. I would be very interested in evidence to the contrary.
Consider ion channels such as the Axon Na+ Channel, the proton pore of
the V-Type ATPases, or lac permease.
No matter what you do, somebody always knew that you would...
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