[Keith D. Wilkinson]

In message 
> From: pmr1716 at ggr.co.uk ("Peter Murray-Rust")
> Subject: Effect of pressure on enzyme reactions
> Date: 21 Jul 93 17:46:30 GMT
> Sender: list-admin at daresbury.ac.uk
> Original-To: proteins at uk.ac.daresbury
> 
> I'd be grateful for any information about whether high-pressure can affect 
> (a)
> the speed and/or (b) the equilibrium of an enzyme-catalysed reaction, and if
> so, what pressures are required in practice to make a useful contribution.  
> If
> this is a well-researched field, I'd be very grateful for pointers to 
> reviews.
> 
> 	Thanks,
> 
> 	Peter
> 
Try papers by Gregorio Weber at the University of Illinois.  His work centered 
on the effectcs of pressure on subunit dissociation, but he may reference 
effects on catalysis directly.  The equilibrium effect should be small but 
calculable from first principles.