Searching a sequence in Brookhaven Protein Data Bank...

Daniel M. Doran, PRTC, phone 88270 dorand at rocbi.DNET.roche.com
Tue Mar 2 06:16:33 EST 1993


> I am trying to search for five or more residues amino acid on all
> proteins that the structures have been found. The results then can prove
> that "one sequence one structure" is correct or not...

       That question was looked into years ago.  See

       W. Kabsch and C. Sander in PNAS 81:1075 (1984)
       I.A. Wilson, et al. in PNAS 82: 5255 (1985)

       The short answer is that identical sequences can can assume
       different secondary structures.

       Dan.

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  Daniel M. Doran, Ph.D.

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