Enzymes as mechanical devices

nvett at ac.dal.ca nvett at ac.dal.ca
Wed May 12 08:50:40 EST 1993


Hi all,
	I was wondering what everyone out there thinks about the recent article 
by R.J.P.Williams (TIBS, April 1993) on enzymes as mechanical devices.  I did
not think that it was an entirely new concept, especially for people who 
appreciate protein structure, but I think it is a very elegant elaboration
of the conformational changes on an enzyme molecule during catalysis.  I would
like to initiate a discussion on this if anyone is interested--to get a general
idea of what you people think.  Thanks a lot. 


Nat Vettakkorumakankav
Department of Biochemistry



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