Would a consensus sequence form an active protein?

Cornelius Krasel krasel at alf.biochem.mpg.de
Wed Mar 2 12:18:34 EST 1994


Rafael N Szeinfeld (szeinfel at FOX.CCE.USP.BR) wrote:

: 	Instead of making a "consensus sequence protein" making random
: mutations in one protein you'll have the same result. These brings the
: advantage that you have the 3d structure (of the protein before mutated) and 
: also that a lot of work was already done with random mutations.

Isn't that roughly what B. Matthews is doing with lysozyme?

--Cornelius.

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/* Cornelius Krasel, Abt. Lohse, Genzentrum, D-82152 Martinsried, Germany */
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/* "People are DNA's way of making more DNA." (Edward O. Wilson, 1975)    */



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