Binding of substrates to kinases

Neal Gliksman Gliksman at uncvx1.oit.unc.edu
Fri Sep 30 12:15:41 EST 1994


I have heard that some kinase substrates have an increased affinity for
their kinase when the phosphorylated ser, thr or tyr is replaced with
an alanine.  Is this true and if so, are there references to this?

     Neal Gliksman
     Cell Biology Department
     Duke University Medical Center

     Gliksman at UNCVX1.OIT.UNC.EDU



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