HELP!!! Protein Graphics!!

John Kuszewski johnk at loglady.ninds.nih.gov
Wed Jan 25 16:02:03 EST 1995


In article <3g5b3v$r68 at lyra.csx.cam.ac.uk>, owde100 at bioc.cam.ac.uk (Orhan Ertughrul) writes:
|> In article <3g4ku9$83s at news.iastate.edu>, pedro at iastate.edu (Pedro M Coutinho) writes:
|>  > 
|>  > Hi!
|>  > 
|>  > In article <1995Jan24.173624.8430 at alw.nih.gov>, johnk at spasm.niddk.nih.gov (John Kuszewski) writes:
|>  > |> In article <3g18fo$no3 at bigblue.oit.unc.edu>, fisher at radonc.unc.edu (Robert Fisher) writes:
|>  > |> |> HELP!!!!  I need to find a program that will generate PDB code if
|>  > |> |> given a protein sequence. 
|>  > |> 
|>  > |> Aren't we all, brother, aren't we all.
|>  > 
|>  > If you protein is homologous to one of the proteins present in the PDB
|>  > why don't you try the Swiss-Model Server ? The URL is
|>  > 
|>  > http://expasy.hcuge.ch/swissmod/SWISS-MODEL.html
|>  > 
|>  > Take time to analyze the results but if you just need a quick
|>  > structure of your protein this works fine!
|>  > 
|>  > You get your model back in less than 30 minutes by email !...
|>  > 
|>  
|> Remember though that it is only a model! Sometimes it's possible
|> to miss things even in crystal structures because the crystal 
|> latice may cause a protein to adopt a position that hides features.
|> Recently molecular dynamic work on a protein (I forget which one) 
|> revealed a channel to the active site that wasn't obvious from
|> the crystal structure for the previous reason. 

Of course, this is one thing that we NMR people don't have
to worry about ;-)

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John Kuszewski                     ||  |/  /|  ||      
johnk at spasm.niddk.nih.gov          ||  /  /||  ||
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that's MISTER protein G to you!     |/__/|      |
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