Help with CD data analysis.

gc genecutl at
Mon Sep 11 13:20:53 EST 1995

In article <43159f$rod at>, njh at wrote:

> Hi,
> I have just made my first tentative steps into the world of circular
dichroism and I am now 
> looking for any information on interpreting those squiggly lines!! Does
anyone know of any 
> article or review or basic introduction to the interpretation of CD
data? What are the 
> significant wavelengths for both proteins and RNA? I am investigating an
RNA-binding protein 
> and looking for changes on binding in both the protein and the RNA.
> Any help appreciated. Thanks.
> Nigel
> njh at

The generic answer to that question is look in any basic protein textbook
and you can find that info.  As a followup to that, does anybody know of
any software to deconvolute CD spectra to get percent helix and sheet?



...doom is like the handle of a pot,              
it's there, know it, have ice in your            
tea, marry, have children, visit your 
dentist, do not scream at night even    genecutl at
if you feel like screaming... -cb

More information about the Proteins mailing list