Raising antibodies to BSA conjugate
satish at a.chem.upenn.edu
Fri Jul 26 00:26:00 EST 1996
I intend to raise polyclonals against a small molecule that I
can conjugate to BSA. The small molecule forms a Schiff base with lysine
residues of BSA. Will the Schiff base be stable for raising antibodies.
I could presumably stabilize the linkage by reduction with borohydride,
but may end up with toxic boron end-products. Does anyonoe have experience
with this situation?
email- goldbej at jkdec.rockefeller.edu
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