GroEL structure

Jeff Seale seale at bioc02.uthscsa.edu
Wed Mar 13 12:07:19 EST 1996


R.K. Scopes wrote:
> 
> "R.K. Scopes" <R.Scopes at latrobe.edu.au> wrote:
> 
> about the structure of GroEL. Specifically, does it contain
>  disulfide bonds.
> 
> I was wrong:  E. coli GroEL does has 6 cysteines; it is a thermophilic
> GroEL that has none.  Nevertheless, as an intracellular protein, all
> cysteines should be free and reduced.
> Bob Scopes

E. coli GroEL contains 3 cysteines/monomer - none of which form
disulphides.

-Jeff



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