Product binding sites on proteins

Ron Tate rtate at
Thu May 2 15:40:03 EST 1996

William P. Tschantz wrote:
> Hi
> I am looking for examples of proteins which have two product binding
> sites (the same product) if such a protein exists.  For example a protein
> which has one binding site where the product is formed and then is
> transferred to a second site on the enzyme.  I know this sounds kind of
> weird but i am trying to make sense of the data i have.  The only way i
> can explain it is if there is a second site present on the enzyme.  I can
> think of no examples except for ribosomes, which is not quite what i am
> looking for.
> Any help is greatly appreciated.
> Thanks
> Bill

Check out Pyruvate Dehydrogenase or any of the alpha-keto 
>Ron Tate                                                                   
>Lab of Franklin Leach
>Dept. of Biochem. & Molecular Biology
>Oklahoma State University rtate at
(405) 744-9326

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