Membrane-impermeable Reducing Agents

Michael Daws Michael.Daws at
Mon May 6 07:00:55 EST 1996

I am looking to reduce disulphide bonds outside of cells without 
affecting internal disulphides.  Is there a reducing agent I can use 
which is membrane impermeable.  Alternatively is there an oxidising 
agent that is membrane impermeable?

Mike Daws

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