Zn fingers in protein-protein interaction

[cok at mole.bio.cam.ac.uk]

> Peter Hohenstein writes:
> Somebody once told me that Zn fingers not only have DNA binding activity,
> but that they can also be involved in protein-protein interactions.
> However, I cannot find any references on this. Does anybody have any
clues on this?
> 
> 
> ---------------

An ARF1-GAP, associated with the Golgi, with a single zinc finger motif
which is necessary for GAP activity. 

See Cukierman et al., Science 270:1999 (1995).

Cahir O'Kane, cok at mole.bio.cam.ac.uk

-- 
Cahir O'Kane, Dept of Genetics, Univ. of Cambridge, UK
cok at mole.bio.cam.ac.uk