bcg0197 at queens-belfast.ac.uk
Tue May 21 10:19:29 EST 1996
In article <1996May20.103007.18684 at leeds.ac.uk>, bmbrl at biovax.leeds.ac.uk writes:
> I was wondering if anyone out there knows how best to describe antibodies
> raised to synthetic peptides. I know that the general description is
> site-directed or anti-peptide antibodies but I am trying to come up with a
> brief description which encapsulates the advantages of using these antibodies.
> Basically, they are polyclonal antibodies but as they are raised to discrete
> regions of the protein of interest (in my case approx. 15 residues) they can
> be considered to recognise a single antigenic determinant. Therefore, I call
> them "monospecific polyclonal antibodies". However, somebody has pointed out
> the possible confusion this generates, as it implies the antibodies recognise
> an antigen that is present in only a single species of animal (monospecific).
> Would "monovalent polyclonal antibodies" be a better description??
> Thanks in advance
How about epitope-directed antibodies?
Andrew Wallace, Ph.D.
School of Biology and Biochemistry
The Queen's University of Belfast Tel. +44-1232-335786
97 Lisburn Road Fax +44-1232-236505
Belfast BT9 7BL a.wallace at queens-belfast.ac.uk
Northern Ireland (UK) http://www.qub.ac.uk/b&bchem/rbiochem.htm
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