Diff. between intrinsic/extrinsic cell membrane proteins
Dima Klenchin
klenchin at facstaff.wisc.edu
Sat Nov 2 20:41:13 EST 1996
In article <bill-0211962041410001 at peacocks.demon.co.uk>, bill at peacocks.demon.co.uk wrote:
#PLease could someone tell me whether proteins found within cell membranes
#which penetrate the membrane but do not span the entire membrane are
#classed as intrinsic or extrinsic proteins; reference book s seem split
#over this.
This is just a matter of definition not worth to think about.
IMO, it's better to use "functional" definition, one possible
example of which is extraction with ~ 6 M urea.
"True" membrane proteins (embedded in the membrane) cannot
be extracted since urea does not dissolve membrane bilyaer.
- Dima
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