Bis-tris-propane: temp. coeff. (dpKa/dT) ??

Dima Klenchin klenchin at
Wed Sep 4 18:29:37 EST 1996

In article <322DF927.7352 at>,
   Achim Recktenwald <achim at> wrote:
->Hi all,
->I am looking for the temperature coefficient(s) [dpKa/dT] of the
->'bis-tris-propane' = 1,3-bis[tris(hydroxymethyl)methylamino]propane 
->for some enzyme kinetic experiments.  
->According to the supplier (Sigma) it has the pKa-values:
->pKa1=6.8 and pKa2=9.0 at T=25C.

For pKa1, standard conditions: -0.016.
Sorry, no info on pKa2.

- Dima


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