Looking for transcription factors

Leemor Joshua-Tor leemor at CSHL.ORG
Wed Jan 15 10:29:50 EST 1997


>Hi there,
>
>Does anybody have a complete list of DNA binding proteins (PDB entry codes)
>of which the crystal structure has been submitted to the PDB database at
>Brookhaven ? SCOP has not classified proteins according to the ability to
>bind DNA. Therefore, it is difficult to find all transcription factors with
>known #D structure.
>
>
>Thanx in advance
>
>Michael Vork


Try the NDB (Nucleic Acid Data Base) at http://ndbserver.rutgers.edu/
They have a compilation of all protein/DNA complexes. I am not sure
if they would also have proteins that bind DNA which weren't in
a complex. Another possibility is to search the PDB at http://www.pdb.bnl.gov/
using DNA binding protein as key words.

Good luck.

  -Leemor



*******************************************************************
  Leemor Joshua-Tor, Ph.D.
  Assistant Investigator
  Keck Structural Biology
  Cold Spring Harbor Laboratory           Tel. (516) 367 8821
  1 Bungtown Road                         Fax  (516) 367 8873
  Cold Spring Harbor, NY 11724            e-mail: leemor at cshl.org
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