Where do I draw the line in a protein family?

Mr. M.J. Lush mlush at hgmp.mrc.ac.uk
Fri Jul 25 05:27:45 EST 1997


        I've been genehunting with my pet protein sequence
and have been fortunate enough to have a putative family of 12
hypothetical and three 'real' proteins in organisms running
from Potato through E. coli,  C. elegans,  Drosophila and all the
way down to Man ;-)
 
        Most of the sequences were found by standard BLAST searches,
but some came up from profilesearches using an alignment of the well
concerved active site (using the sequences I'm really sure of!).
 
        Could anyone advise on the pitfalls/papers/reviews I should
look out for?
 
TIA^6
 

-- 

Michael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
NPC rights activist           |      Nameless Abominations are people too.



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