Guanidinium hydrochloride

SFord4395 sford4395 at
Wed Mar 12 16:09:16 EST 1997

Heavy question!!

I would imagine that the nitrogen and carbonyl groups on the Gd.HCl
interupts the hydrogen bonding that helps hold the native state
confornation together. They will also be other entropic effects but I
don't know enough about protein thermodynamics to comment.

Any protein thermodynamic bods out there? Stephen ?



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