Leu Zipper Blues

Pete pkursula at cc.oulu.fi
Fri Mar 21 03:12:29 EST 1997

Suppose that you found out that your protein has a leucine zipper
structure and forms tight dimers... Is possible to separate these into
monomers? On the other hand, if one is studying the function/ligands of
the protein in question, is this feasible? Are these proteins present in
the cell ONLY as dimers or is there an equilibrium that would enable the
monomeric form to also have a distinct function. Any good ideas and
references are strongly appreciated!

This is your change to prove that you really are a protein specialist.

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