Tom Bickle bickle at
Tue Mar 25 09:26:09 EST 1997

In article <tyr-2-2203971058510001 at>,
tyr-2 at (Karl Fischer) wrote:

> In article <5gv4f2$9rp$1 at>, scotbean at (Scott
> Bean) wrote:
> > I'm looking for references dealing with the CMC of SDS and the effects that 
> > buffer salts might have on the CMC.  Can anyone give some ref's to
start with?
> > Is there any general rules concerning the CMC of detergents and ionic
> strength 
> > of a buffer? (e.g Does the CMC always decrease if you increase ionic
> strenth). 

There is a useful booklet on detergent properties issued by Calbiochem.
For SDS, it lists a CMC of 7-10 mM in low or no salt and 1-2 mM at 100-200
mM salt.

Tom Bickle, Department of Microbiology, Biozentrum, Basel University
Klingelbergstrasse 70, CH-4056 Basel, Switzerland.
+4161 267 2120, Fax: +4161 267 2118  bickle at

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