cleavage of protein in SDS-gel

CRC Institute for Cancer Studies noone at
Wed Sep 17 09:33:42 EST 1997


I am looking for a method to cleave a protein (ca. 400 kDa) in a gel. Due
to the size, I thought of BrCN. However, all methods I could get hold of
involved electroelution (which I think won't work with such a protein).
Maybe AspN or ArgC would be alternatives?

Thanks in advance,

Peter at

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