transmembrane domains

Simon Hoffenberg simonh at bcm.tmc.edu
Fri Mar 27 19:18:46 EST 1998


Dear netters,

If there is more than 1 transmembrane domain in a protein, what are the
combinations? For example, 7 domains in receptors coupled to G-proteins or
12 in adenylate cyclase. Is it possible to have 2 or 8-9 domains? If these
numbers are not allowed by Mother Nature, does it mean that these proteins
are in fact 1 and 7 transmembrane domain proteins, respectively?

Simon Hoffenberg
Baylor College of Medicine
Houston, TX
simonh at bcm.tmc.edu



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