transmembrane domains

[Steve Alexander]

Simon Hoffenberg wrote:
> 
> Dear netters,
> 
> If there is more than 1 transmembrane domain in a protein, what are the
> combinations? For example, 7 domains in receptors coupled to G-proteins or
> 12 in adenylate cyclase. Is it possible to have 2 or 8-9 domains? 

P2X-purinoceptors are thought to be ion channels made up of pentamers
with 2 TM domains.

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Steve Alexander, Biomedical Sciences,
University of Nottingham Medical School,
Nottingham NG7 2UH, UK
WWW http://www.nottingham.ac.uk/biomedsci/
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